Xyosted – Testosterone Enanthate Auto-Injector

Xyosted is a prescription medicine used as hormone replacement therapy in adult men who have low or no testosterone due to certain medical conditions.
Key Features
- First FDA-approved subcutaneous testosterone enanthate auto-injector for once-weekly at-home therapy.
- Available in three dosage strengths: 50 mg, 75 mg, and 100 mg.
- Designed for easy self-administration with a single-dose, disposable QuickShot® auto-injector.
Usage Instructions
The typical starting dosage of Xyosted for adults with low testosterone levels is 75 mg injected once per week. After 6 weeks, testosterone levels are checked, and the dosage may be adjusted accordingly.
Warnings and Precautions
Boxed warning: Risk of increased blood pressure
Xyosted has a boxed warning about the risk of increased blood pressure. Increased blood pressure caused by Xyosted can result in serious heart problems, which can be life-threatening.
Common Side Effects
- Headache
- Back pain
- Acne
- Injection site bruising
- Increased hematocrit
- Increased prostate-specific antigen (PSA)
Scientific References
- Antares Pharma. (2018). Antares Receives FDA Approval of Xyosted™ (Testosterone Enanthate) Injection for Testosterone Replacement Therapy in Adult Males. Retrieved from GlobeNewswire
- Healthline. (n.d.). Xyosted: Uses, Dosage, Side Effects & Warnings. Retrieved from Healthline
- Drugs.com. (n.d.). Xyosted: Uses, Dosage, Side Effects & Warnings. Retrieved from Drugs.com
- Medical News Today. (n.d.). Xyosted side effects: Mild to serious and how to manage them. Retrieved from Medical News Today