Intrarosa (DHEA) Vaginal Insert for Menopause Relief

Intrarosa (Prasterone) – DHEA Vaginal Insert for Menopause Symptoms

Intrarosa (Prasterone) – DHEA Vaginal Insert for Menopause Symptoms

What is Intrarosa?

Intrarosa is a prescription vaginal insert that contains prasterone, also known as dehydroepiandrosterone (DHEA). It is used to treat moderate to severe vaginal atrophy, specifically symptoms like dryness and pain during sex (dyspareunia), which are common in postmenopausal women.

How Does Intrarosa Work?

Prasterone is an inactive steroid that converts into active sex hormones (estrogens and androgens) within the cells of vaginal tissue. This localized conversion helps restore the thickness, elasticity, and lubrication of vaginal tissue without significantly affecting systemic hormone levels.

Uses of Intrarosa

  • Treatment of vaginal dryness caused by menopause
  • Relief from pain during sexual intercourse (dyspareunia)
  • Improves vaginal health by increasing tissue strength and moisture

How to Use Intrarosa

Intrarosa comes as a small, bullet-shaped insert. It is inserted into the vagina once daily at bedtime using an applicator provided with the product. Always follow your healthcare provider’s instructions for proper use.

Benefits of Intrarosa

  • Non-estrogen option for treating vaginal symptoms
  • Minimal impact on hormone levels in the bloodstream
  • Improves quality of life for postmenopausal women

Possible Side Effects

  • Vaginal discharge
  • Abnormal Pap smear results
  • Vaginal bleeding or spotting

If you experience severe side effects or allergic reactions, consult your doctor immediately.

Precautions

  • Not recommended for women with undiagnosed vaginal bleeding
  • Discuss risks if you have a history of hormone-sensitive cancers
  • Use under the supervision of a healthcare professional

FAQs

Is Intrarosa safe for long-term use?

Clinical studies suggest that Intrarosa is generally well-tolerated for long-term use, but regular monitoring is advised.

Does Intrarosa affect hormone levels in the body?

It mainly acts locally within vaginal tissues and has minimal impact on circulating hormone levels.

Can I use Intrarosa with other vaginal treatments?

Consult your healthcare provider before combining treatments to avoid potential interactions.

Sources / Scientific References

  • FDA. (2016). Intrarosa Prescribing Information.
  • Deecher, D. C. (2005). “The role of the DHEA in postmenopausal health.” Maturitas, 51(2), 169–180.
  • Simon JA et al. (2018). “Long-term efficacy and safety of prasterone for the treatment of dyspareunia.” Menopause, 25(5): 520–526.

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