Estring Vaginal Ring – Estrogen Therapy for Dryness

Estring Vaginal Ring – Low-Dose Estrogen for Relief

Estring – Estradiol Vaginal Ring for Menopause Relief

What is Estring?

Estring is a soft, flexible vaginal ring that slowly releases estradiol (a form of estrogen) over 90 days. It is used to treat vaginal symptoms of menopause like dryness, burning, and painful intercourse.

How Does Estring Work?

Estring delivers a steady, low dose of estrogen directly to the vaginal tissues. This helps restore moisture, elasticity, and reduce discomfort associated with thinning vaginal walls (vaginal atrophy).

Who Can Use Estring?

  • Postmenopausal women with vaginal symptoms
  • Women looking for local (not systemic) hormone treatment
  • Patients who prefer long-lasting therapy without daily application

Benefits of Estring

  • Lasts for up to 90 days with one application
  • Delivers consistent estrogen levels locally
  • Minimal hormone absorption into the bloodstream
  • Improves vaginal comfort and sexual health

How to Use Estring

Estring is inserted into the vagina, where it stays continuously for 3 months. Your doctor may show you how to insert or remove it, or do it during an appointment. It should be replaced every 90 days if continued therapy is needed.

Possible Side Effects

  • Vaginal discharge or irritation
  • Pelvic pain
  • Headache or nausea
  • Breast tenderness

Though rare, estrogen therapy can increase the risk of blood clots, stroke, or uterine cancer. Talk to your doctor if you have a history of such conditions.

Precautions & Warnings

  • Not for use during pregnancy or breastfeeding
  • Not recommended for women with certain cancers or unexplained vaginal bleeding
  • Routine exams and monitoring are advised during long-term use

Frequently Asked Questions

Is Estring better than creams or tablets?

It depends on your preference. Estring offers consistent hormone release and less frequent dosing, while creams or tablets are applied more often.

Will I feel the ring inside?

Most women do not feel it after insertion. If discomfort continues, consult your doctor for proper placement.

Does it affect my partner during intercourse?

Some partners may feel it during sex, but it’s generally not painful or problematic.

Sources / Scientific References

  • FDA. Estring (estradiol vaginal ring) [Prescribing Information]. FDA Label
  • North American Menopause Society. “Estrogen Therapy for Vaginal Symptoms.” 2022 Guidelines.
  • Simon JA et al. (2003). “Vaginal Estrogen Ring for Postmenopausal Atrophy.” Obstet Gynecol, 102(3), 563–568.
  • Portman DJ, Gass ML. (2014). “Genitourinary Syndrome of Menopause.” Menopause, 21(10):1063–1068.

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