What is Estrace Cream?

Estrace Cream is a prescription vaginal cream that contains estradiol, a form of estrogen hormone. It is primarily used to treat vaginal symptoms of menopause such as dryness, itching, and painful intercourse caused by thinning of vaginal tissues (atrophy).

How Does Estrace Work?

During menopause, estrogen levels drop significantly. Estrace replenishes local estrogen in the vaginal tissues. This helps rebuild and maintain the thickness, elasticity, and natural moisture of the vaginal lining.

Indications and Uses

• Relief from vaginal dryness and irritation
• Treatment for painful sexual intercourse (dyspareunia)
• Improves overall vaginal health post-menopause

How to Use Estrace Cream

Estrace is applied directly inside the vagina using a special applicator. It is typically used once daily for 1 to 2 weeks, then reduced to 1 to 3 times per week, as directed by your healthcare provider.

Benefits of Estrace Cream

• Directly targets vaginal symptoms
• Lower systemic hormone absorption compared to oral estrogen
• Improves comfort and intimacy during sex

Possible Side Effects

• Vaginal discharge or spotting
• Breast tenderness
• Headache or nausea
• Rarely, risk of blood clots or stroke (with long-term use)

Always discuss potential risks and benefits with your doctor, especially if you have a history of hormone-related conditions.

Precautions

• Not for use during pregnancy or breastfeeding
• Use with caution if you have a history of breast, uterine, or ovarian cancer
• Regular pelvic exams and monitoring are recommended

FAQs

Is Estrace safe for long-term use?

It can be used long-term under medical supervision, but the lowest effective dose should always be used.

Can Estrace be used with other hormone therapies?

Yes, but only if prescribed. Combining therapies may increase risk of side effects.

Does Estrace increase the risk of cancer?

Long-term estrogen use may increase the risk of certain cancers. Regular screening and checkups are essential.