Addyi – Flibanserin for Low Libido in Women
The first FDA-approved daily pill to treat low sexual desire in premenopausal women
What is Addyi?
Addyi (flibanserin) is a non-hormonal prescription medication approved by the FDA to treat Hypoactive Sexual Desire Disorder (HSDD) in premenopausal women. It’s sometimes referred to as the “female Viagra,” although it works very differently.
How Does It Work?
Flibanserin works by targeting neurotransmitters in the brain, including serotonin and dopamine. It is thought to restore balance among these chemicals, which may improve sexual desire over time. (Paraphrased from official prescribing information)
Who Can Use Addyi?
Addyi is for premenopausal women diagnosed with acquired, generalized HSDD — meaning low sexual desire that is not due to other medical, psychological, or relationship issues.
How is Addyi Taken?
The recommended dose is 100 mg taken once daily at bedtime. Taking it during the day may increase the risk of side effects like low blood pressure or fainting. (Based on FDA prescribing label)
Benefits of Addyi
- May increase sexual desire in some women
- Non-hormonal treatment option
- Convenient oral tablet taken daily
Side Effects and Risks
Common side effects include:
- Dizziness
- Fatigue
- Nausea
- Dry mouth
- Sleep disturbances
⚠️ Important: Do not consume alcohol while taking Addyi, as it may cause dangerously low blood pressure and fainting. (Direct warning from FDA label)
Who Should Avoid Addyi?
- Postmenopausal women
- Men
- Women with liver problems
- Anyone taking certain medications (CYP3A4 inhibitors)
Is Addyi Effective?
Clinical studies show a modest improvement in sexual desire for some women. It may not work for everyone, and the benefits need to be weighed against possible side effects. (Paraphrased from clinical trials data)
Conclusion
Addyi represents a major step forward in women’s sexual health by offering an option for those struggling with low libido. Like any medication, it requires medical supervision and may not be right for everyone.
Sources / Scientific References:
- U.S. FDA – Addyi (Flibanserin) Information
- FDA Prescribing Information for Addyi (2015)
- Simon JA, Kim NN, Davis SR. “Flibanserin for HSDD in Premenopausal Women.” J Sex Med, 2016.
- PubMed – Flibanserin review article